Is it possible to select multiple hyperlinks on a page and change their properties all at once. Or another option, be able to change the hyperlink properties in the Settings tab. By default, all of the hyperlinks are locked and I can only change their properties one at a time. I would like to change all of them as a group once.
That is a great feature request! Currently, we only allow changing the properties of 1 annotation at once. If you are creating the hyperlinks, you can change the default properties, so all future hyperlinks are created with those settings.

Another thing - are you talking about changing the defaults for the PDF hyperlinks, or the hyperlink annotation?